E-Cadherin Regulates HIF1-α In Vitro in Induced 3D Spheroid Models of Human Breast Cancer Through Both mTOR and Notch1 Signaling

<b>Background</b>: Both spontaneous and induced 3D spheroid models are among many in vitro models that recapitulate aspects of in vivo cancers. Although numerous studies have described the spatiotemporal relevance of these 3D models, there has been a paucity of studies investigating the signaling pa...

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主要な著者:	Yin Ye, Dollada Srisai, Sanford H. Barsky
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2025-11-01
シリーズ:	Biomedicines
主題:	3D spheroidgenesis induced spheroidgenesis spontaneous spheroidgenesis HIF-1α PI3K/AKT/mTOR signaling Notch1 signaling
オンライン･アクセス:	https://www.mdpi.com/2227-9059/13/12/2890
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