Detection of allele-specific expression in spatial transcriptomics with spASE
Abstract Spatial transcriptomics technologies permit the study of the spatial distribution of RNA at near-single-cell resolution genome-wide. However, the feasibility of studying spatial allele-specific expression (ASE) from these data remains uncharacterized. Here, we introduce spASE, a computation...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2024-07-01
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| Schriftenreihe: | Genome Biology |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s13059-024-03317-4 |
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