Detection of allele-specific expression in spatial transcriptomics with spASE

Abstract Spatial transcriptomics technologies permit the study of the spatial distribution of RNA at near-single-cell resolution genome-wide. However, the feasibility of studying spatial allele-specific expression (ASE) from these data remains uncharacterized. Here, we introduce spASE, a computation...

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Prif Awduron:	Luli S. Zou, Dylan M. Cable, Irving A. Barrera-Lopez, Tongtong Zhao, Evan Murray, Martin J. Aryee, Fei Chen, Rafael A. Irizarry
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2024-07-01
Cyfres:	Genome Biology
Pynciau:	Spatial transcriptomics Allele-specific expression
Mynediad Ar-lein:	https://doi.org/10.1186/s13059-024-03317-4
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