Feasibility of Ex Vivo Ligandomics
We developed ligandomics for the in vivo profiling of vascular ligands in mice, discovering secretogranin III (Scg3) as a novel angiogenic factor that selectively binds to retinal vessels of diabetic but not healthy mice. This discovery led to the development of anti-Scg3 therapy for ocular vasculop...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI AG
2025-01-01
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| Series: | Biomolecules |
| Assuntos: | |
| Acceso en liña: | https://www.mdpi.com/2218-273X/15/1/145 |
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