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P-selectin, carcinoma metastasis and heparin: novel mechanistic connections with therapeutic implications

Metastasis is a multistep cascade initiated when malignant cells penetrate the tissue surrounding the primary tumor and enter the bloodstream. Classic studies indicated that blood platelets form complexes around tumor cells in the circulation and facilitate metastases. In other work, the anticoagula...

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Bibliografiske detaljer
Principais autores: Varki A., Varki N.M.
Format: Artigo
Sprog:Inglês
Udgivet: Associação Brasileira de Divulgação Científica 2001-01-01
Serier:Brazilian Journal of Medical and Biological Research
Fag:
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600003
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