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Hypoxia-induced NFATc3 deSUMOylation enhances pancreatic carcinoma progression

Abstract The transcriptional regulator nuclear factor of activated T-cells, cytoplasmic 3 (NFATc3) is constitutively activated in several cancer types and plays important roles in cancer development and progression. Heavily phosphorylated NFATc3 resides in the cytoplasm of resting cells, and dephosp...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yingying Tong, Zheng Zhang, Yurong Cheng, Jing Yang, Cong Fan, Xuyang Zhang, Jiandong Yang, Li Wang, Dong Guo, Dong Yan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2022-04-01
Cyfres:Cell Death and Disease
Mynediad Ar-lein:https://doi.org/10.1038/s41419-022-04779-9
Tagiau: Ychwanegu Tag
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