SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation

Abstract Background Neoadjuvant radiotherapy has been used as the standard treatment of colorectal cancer (CRC). However, radiotherapy resistance often results in treatment failure. To identify radioresistant genes will provide novel targets for combined treatments and prognostic markers. Methods Th...

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Principais autores:	Tingting Liu, Hang Wang, Yuanyuan Chen, Zhijie Wan, Zhipeng Du, Hui Shen, Yue Yu, Shengzhe Ma, Ying Xu, Zhuqing Li, Nanxi Yu, Fangxiao Zhang, Kun Cao, Jianming Cai, Wei Zhang, Fu Gao, Yanyong Yang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2023-09-01
סדרה:	Journal of Experimental & Clinical Cancer Research
נושאים:	Cancer resistance SENP5 deSUMOylation DNA damage repair
גישה מקוונת:	https://doi.org/10.1186/s13046-023-02789-9
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!