Escherichia coli β-clamp slows down DNA polymerase I dependent nick translation while accelerating ligation.
The nick translation property of DNA polymerase I (Pol I) ensures the maturation of Okazaki fragments by removing primer RNAs and facilitating ligation. However, prolonged nick translation traversing downstream DNA is an energy wasting futile process, as Pol I simultaneously polymerizes and depolyme...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science (PLoS)
2018-01-01
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| श्रृंखला: | PLoS ONE |
| ऑनलाइन पहुंच: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199559&type=printable |
| टैग: |
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