Glutaminolysis is associated with mitochondrial pathway activation and can be therapeutically targeted in glioblastoma

Abstract Background Glioblastoma is an aggressive cancer that originates from abnormal cell growth in the brain and requires metabolic reprogramming to support tumor growth. Metabolic reprogramming involves the upregulation of various metabolic pathways. Although the activation of specific metabolic...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Kenji Miki, Mikako Yagi, Ryusuke Hatae, Ryosuke Otsuji, Takahiro Miyazaki, Katsuhiro Goto, Daiki Setoyama, Yutaka Fujioka, Yuhei Sangatsuda, Daisuke Kuga, Nayuta Higa, Tomoko Takajo, Yonezawa Hajime, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Yuya Kunisaki, Takeshi Uchiumi, Koji Yoshimoto
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2024-11-01
Sarja:	Cancer & Metabolism
Aiheet:	Glioblastoma Glutaminolysis Mitochondria Metabolic changes
Linkit:	https://doi.org/10.1186/s40170-024-00364-0
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