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Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis

ABSTRACT Ovarian cancer is the leading cause of gynecological malignancy-related deaths. Current therapies for ovarian cancer do not provide meaningful and sustainable clinical benefits, highlighting the need for new therapies. We show that the histone H3K79 methyltransferase disruptor of telomeric...

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Xehetasun bibliografikoak
Egile Nagusiak: Suresh Chava, Suresh Bugide, Yvonne J. K. Edwards, Romi Gupta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2021-07-01
Saila:Oncogenesis
Sarrera elektronikoa:https://doi.org/10.1038/s41389-021-00339-6
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