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Effect of Synchronous Versus Sequential Regimens on the Pharmacokinetics and Biodistribution of Regorafenib with Irradiation

This study was performed to evaluate the interaction between conventional or high-dose radiotherapy (RT) and the pharmacokinetics (PK) of regorafenib in concurrent or sequential regimens for the treatment of hepatocellular carcinoma. Concurrent and sequential in vitro and in vivo studies of irradiat...

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Autori principali: Tung-Hu Tsai, Yu-Jen Chen, Li-Ying Wang, Chen-Hsi Hsieh
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-03-01
Serie:Pharmaceutics
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Accesso online:https://www.mdpi.com/1999-4923/13/3/386
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