Formulation of Liver-Specific PLGA-DY-635 Nanoparticles Loaded with the Protein Kinase C Inhibitor Bisindolylmaleimide I

Bisindolylmaleimide I (BIM-I) is a competitive pan protein kinase C inhibitor with anti-inflammatory and anti-metastatic properties, suggested to treat inflammatory diseases and various cancer entities. However, despite its therapeutic potential, BIM-I has two major drawbacks, i.e., it has a poor wa...

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Detalhes bibliográficos

Principais autores:	Blerina Shkodra, Adrian T. Press, Antje Vollrath, Ivo Nischang, Stephanie Schubert, Stephanie Hoeppener, Dorothee Haas, Christoph Enzensperger, Marc Lehmann, Petra Babic, Kay Jovana Benecke, Anja Traeger, Michael Bauer, Ulrich S. Schubert
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-11-01
Colecção:	Pharmaceutics
Assuntos:	active targeting bisindolylmaleimide I drug delivery liver disease nanoparticle formulation PKC
Acesso em linha:	https://www.mdpi.com/1999-4923/12/11/1110
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