Thorough molecular configuration analysis of noncanonical AAV genomes in AAV vector preparations
The unique palindromic inverted terminal repeats (ITRs) and single-stranded nature of adeno-associated virus (AAV) DNA are major hurdles to current sequencing technologies. Due to these characteristics, sequencing noncanonical AAV genomes present in AAV vector preparations remains challenging. To ad...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2024-03-01
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| シリーズ: | Molecular Therapy: Methods & Clinical Development |
| 主題: | |
| オンライン・アクセス: | http://www.sciencedirect.com/science/article/pii/S2329050124000317 |
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