Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface

Abstract CD47/signal‐regulatory protein α (SIRPα) signaling enables malignant cells to evade macrophage‐mediated phagocytosis, offering a promising strategy for cancer therapy via immune checkpoint blockade. However, this strategy is widely debated due to several safety risks revealed by clinical st...

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Autors principals:	Peng‐Cheng Yu, Chen‐Xi Yue, Wen‐Zhong Dong, Cui‐Yun Hao, Yi‐Fan Qiao, Di Liu, Xin Zhang, Qi Zhan, Jia‐Bao Yao, Dong‐Ping Wang, Peng Cao, Ying‐Zhe Fan, Ye Yu
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2026-01-01
Col·lecció:	Advanced Science
Matèries:	cancer immunotherapy CD47 immune checkpoint integrin αvβ3 peptides
Accés en línia:	https://doi.org/10.1002/advs.202501602
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