Knockout of c‐Cbl slows EGFR endocytic trafficking and enhances EGFR signaling despite incompletely blocking receptor ubiquitylation
Abstract Epidermal growth factor receptor (EGFR) activity is necessary and sufficient for corneal epithelial homeostasis. However, the addition of exogenous Epidermal Growth Factor (EGF) does not reliably restore the corneal epithelium when wounded. This is likely due to high levels of endogenous EG...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Wiley
2021-04-01
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| Seria: | Pharmacology Research & Perspectives |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1002/prp2.756 |
| Etykiety: |
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