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Autoimmune lymphoproliferative immunodeficiencies (ALPID) in childhood: breakdown of immune homeostasis and immune dysregulation

Abstract Many inborn errors of immunity (IEI) manifest with hallmarks of both immunodeficiency and immune dysregulation due to uncontrolled immune responses and impaired immune homeostasis. A subgroup of these disorders frequently presents with autoimmunity and lymphoproliferation (ALPID phenotype)....

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Principais autores: Vasil Toskov, Stephan Ehl
פורמט: Artigo
שפה:Inglês
יצא לאור: SpringerOpen 2023-09-01
סדרה:Molecular and Cellular Pediatrics
נושאים:
Autoimmune lymphoproliferative immunodeficiencies
Inborn errors of immunity
Immune dysregulation
Pathogenesis
Targeted therapy
גישה מקוונת:https://doi.org/10.1186/s40348-023-00167-1
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