Genotype-degree of hemolysis correlation in hereditary spherocytosis

Abstract Background Hereditary spherocytosis (HS) is a common inherited hemolytic anemia, caused by mutations in five genes that encode erythrocyte membrane skeleton proteins. The red blood cell (RBC) lifespan could directly reflect the degree of hemolysis. In the present cohort of 23 patients with...

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Bibliografiske detaljer

Principais autores:	Yimeng Shi, Yuan Li, Xiawan Yang, Xiaoxia Li, Guangxin Peng, Xin Zhao, Xu Liu, Yufei Zhao, Jing Hu, Xiangrong Hu, Baohang Zhang, Kang Zhou, Yang Yang, Youzhen Xiong, Jianping Li, Huihui Fan, Wenrui Yang, Lei Ye, Liping Jing, Li Zhang, Fengkui Zhang
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2023-06-01
Serier:	BMC Genomics
Fag:	Hereditary spherocytosis Red blood cell lifespan Degree of hemolysis Levitt’s carbon monoxide breath test Next-generation sequencing
Online adgang:	https://doi.org/10.1186/s12864-023-09364-8
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