Improved haplotype resolution of highly duplicated MHC genes in a long-read genome assembly using MiSeq amplicons

Long-read sequencing offers a great improvement in the assembly of complex genomic regions, such as the major histocompatibility complex (MHC) region, which can contain both tandemly duplicated MHC genes (paralogs) and high repeat content. The MHC genes have expanded in passerine birds, resulting in...

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Ngā kaituhi matua:	Samantha Mellinger, Martin Stervander, Max Lundberg, Anna Drews, Helena Westerdahl
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	PeerJ Inc. 2023-07-01
Rangatū:	PeerJ
Ngā marau:	Haploid genome assembly Amplicon sequencing Major histocompatibility complex MHC diversity Family Linkage analysis
Urunga tuihono:	https://peerj.com/articles/15480.pdf
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!