Network pharmacology, prognostic analysis and experimental validation elucidate the therapeutic mechanism of Dingxiang Guanshitong in esophageal cancer

Abstract This study aimed to investigate the target genes of active components in Dingxiang Guanshitong (DGST) and evaluate their significance in the prognosis of esophageal cancer (EC) through integrated approaches, including network pharmacology, molecular docking, prognostic analysis, and in vitr...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Hao Zhang, Shi-qi Wang, Xiao-qi Chen, Li-qi Li, Yu-hong Zheng, Ya-ling Zhang, Xue-wen Diao, Pei-yu Yan, Yu-ling Zheng
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2025-05-01
Цуврал:	Scientific Reports
Нөхцлүүд:	Dingxiang guanshitong Prognostic target genes Esophageal cancer Network pharmacology Molecular docking Pathway enrichment
Онлайн хандалт:	https://doi.org/10.1038/s41598-025-00910-w
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!