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QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway

Purpose: Heart failure (HF) is a leading cause of morbidity and mortality worldwide, and it is characterized by cardiac hypertrophy and fibrosis. However, effective treatments are not available to block cardiac fibrosis after cardiac hypertrophy. The QiShenYiQi pill (QSYQ) is an effective treatment...

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Principais autores: Gulinigaer Anwaier, Ting-Ting Xie, Chun-Shui Pan, An-Qing Li, Li Yan, Di Wang, Fan-Kai Chen, Ding-Zhou Weng, Kai Sun, Xin Chang, Jing-Yu Fan, Jing-Yan Han, Jian Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-07-01
coleção:Frontiers in Pharmacology
Assuntos:
cardiac fibrosis
pressure overload
FHL2
RP S19
TGF-β1
SMADs
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.918335/full
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