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YangXue QingNao Wan, a Compound Chinese Medicine, Attenuates Cerebrovascular Hyperpermeability and Neuron Injury in Spontaneously Hypertensive Rat: Effect and Mechanism

ObjectiveThe purpose of the study was to explore the effect of YangXue QingNao Wan (YXQNW), a compound Chinese medicine, on cerebrovascular hyperpermeability, neuronal injury, and related mechanisms in spontaneously hypertensive rat (SHR).MethodsFourteen-week-old male SHR were used, with Wistar Kyot...

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Principais autores: Ying-Qian Jiao, Ping Huang, Li Yan, Kai Sun, Chun-Shui Pan, Quan Li, Jing-Yu Fan, Zhi-Zhong Ma, Jing-Yan Han
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-10-01
coleção:Frontiers in Physiology
Assuntos:
hypertension
tight junction
caveolin-1
blood–brain barrier
ATP
microvessel
Acesso em linha:https://www.frontiersin.org/article/10.3389/fphys.2019.01246/full
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