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CRISPR/Cas9-mediated knock out of ITGB6 in human OSCC cells reduced migration and proliferation ability

Abstract Background The treatment of oral squamous cell carcinoma (OSCC) remains challenging and survival rates have not been improved significantly over the past decades. Integrins have been recognized driving the cancer progression and high expression levels cause poor outcomes in patients afflict...

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Autors principals: Maximilian Geyer, Fabian Geyer, Ute Reuning, Sarah Klapproth, Klaus-Dietrich Wolff, Markus Nieberler
Format: Artigo
Idioma:Inglês
Publicat: BMC 2024-06-01
Col·lecció:Head & Face Medicine
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Accés en línia:https://doi.org/10.1186/s13005-024-00437-x
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