Proteomic Alterations and Novel Markers of Neurotoxic Reactive Astrocytes in Human Induced Pluripotent Stem Cell Models

Astrocytes respond to injury, infection, and inflammation in the central nervous system by acquiring reactive states in which they may become dysfunctional and contribute to disease pathology. A sub-state of reactive astrocytes induced by proinflammatory factors TNF, IL-1α, and C1q (“TIC”) has been...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	David Labib, Zhen Wang, Priya Prakash, Matthew Zimmer, Matthew D. Smith, Paul W. Frazel, Lilianne Barbar, Maria L. Sapar, Peter A. Calabresi, Junmin Peng, Shane A. Liddelow, Valentina Fossati
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2022-05-01
Цуврал:	Frontiers in Molecular Neuroscience
Нөхцлүүд:	reactive astrocytes induced pluripotent stem cells proteomics surface markers inflammation neurodegenerative diseases
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.870085/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!