Flower/FLWR-1 regulates neuronal activity via the plasma membrane Ca2+ ATPase to promote recycling of synaptic vesicles

The Flower protein was suggested to couple the fusion of synaptic vesicles (SVs) to their recycling in different model organisms. It is supposed to trigger activity-dependent bulk endocytosis by conducting Ca2+ at endocytic sites. However, this mode of action is debated. Here, we investigated the ro...

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Detalhes bibliográficos

Principais autores:	Marius Seidenthal, Jasmina Redzovic, Jana F Liewald, Dennis Rentsch, Stepan Shapiguzov, Noah Schuh, Nils Rosenkranz, Stefan Eimer, Alexander Gottschalk
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2025-05-01
coleção:	eLife
Assuntos:	plasma membran Ca2+ ATPase synaptic vesicle recycling Ca2+ homeostasis PIP2 endocytosis
Acesso em linha:	https://elifesciences.org/articles/103870
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