Flower/FLWR-1 regulates neuronal activity via the plasma membrane Ca2+ ATPase to promote recycling of synaptic vesicles

The Flower protein was suggested to couple the fusion of synaptic vesicles (SVs) to their recycling in different model organisms. It is supposed to trigger activity-dependent bulk endocytosis by conducting Ca2+ at endocytic sites. However, this mode of action is debated. Here, we investigated the ro...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Marius Seidenthal, Jasmina Redzovic, Jana F Liewald, Dennis Rentsch, Stepan Shapiguzov, Noah Schuh, Nils Rosenkranz, Stefan Eimer, Alexander Gottschalk
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	eLife Sciences Publications Ltd 2025-05-01
Цуврал:	eLife
Нөхцлүүд:	plasma membran Ca2+ ATPase synaptic vesicle recycling Ca2+ homeostasis PIP2 endocytosis
Онлайн хандалт:	https://elifesciences.org/articles/103870
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!