N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors

<p>Abstract</p> <p>Background</p> <p>Pharmacological activation of type-2 metabotropic glutamate receptors (mGlu2 receptors) causes analgesia in experimental models of inflammatory and neuropathic pain. Presynaptic mGlu2 receptors are activated by the glutamate released from astrocytes by means of t...

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Detalhes bibliográficos

Principais autores:	Bernabucci Matteo, Notartomaso Serena, Zappulla Cristina, Fazio Francesco, Cannella Milena, Motolese Marta, Battaglia Giuseppe, Bruno Valeria, Gradini Roberto, Nicoletti Ferdinando
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SAGE Publishing 2012-10-01
coleção:	Molecular Pain
Assuntos:	Cystine/glutamate antiporter N-acetyl-cysteine mGlu2 receptors Analgesia AGS3
Acesso em linha:	http://www.molecularpain.com/content/8/1/77
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