ALT control, delete: FANCM as an anti-cancer target in Alternative Lengthening of Telomeres
Break-induced replication is a specific type of DNA repair that has a co-opted role in telomere extension by telomerase-negative cancer cells. This Alternative Lengthening of Telomeres (or ‘ALT’) is required for viability in approximately 10% of all carcinomas, but up to 50% of the soft-tissue deriv...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis Group
2019-01-01
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| Seria: | Nucleus |
| Hasła przedmiotowe: | |
| Dostęp online: | http://dx.doi.org/10.1080/19491034.2019.1685246 |
| Etykiety: |
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