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HLA Preferences for Conserved Epitopes: A Potential Mechanism for Hepatitis C Clearance

Hepatitis C virus (HCV) infections affect more than 170 million people worldwide. Most of these individuals are chronically infected, but some clear the infection rapidly. Host factors seem to play a key role in HCV clearance, among them the human leukocyte antigen (HLA) class I molecules. Certain H...

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Kaydedildi:
Asıl Yazarlar: Xiangyu eRao, Ilka eHoof, Debbie eVan Baarle, Can eKeşmir, Johannes eTextor
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2015-10-01
Seri Bilgileri:Frontiers in Immunology
Konular:
Hepatitis C virus
sequence conservation
HLA disease association
peptide-MHC binding predictions
CTL responses.
Online Erişim:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00552/full
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