Complementarity of binding motifs is a general property of HLA-A and HLA-B molecules and does not seem to effect HLA haplotype composition

Different HLA haplotypes (i.e., the specific combinations of HLA-A, -B, -DR alleles inherited together from one parent) are observed in different frequencies in human populations. Some haplotypes, like HLA-A1-B8, are very frequent, reaching up to 10% in the Caucasian population, while others are ver...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Xiangyu eRao, Rob J De Boer, Debbie evan Baarle, Martin eMaiers, Can eKesmir
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2013-11-01
Rangatū:	Frontiers in Immunology
Ngā marau:	Haplotypes HLA Antigens Selection, Genetic Bioinformatics & Computational Biology Peptide binding
Urunga tuihono:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00374/full
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!