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PyDamage: automated ancient damage identification and estimation for contigs in ancient DNA de novo assembly

DNA de novo assembly can be used to reconstruct longer stretches of DNA (contigs), including genes and even genomes, from short DNA sequencing reads. Applying this technique to metagenomic data derived from archaeological remains, such as paleofeces and dental calculus, we can investigate past micro...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Maxime Borry, Alexander Hübner, Adam B. Rohrlach, Christina Warinner
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2021-07-01
Schriftenreihe:PeerJ
Schlagworte:
metagenomics
aDNA
ancient DNA
assembly
damage
de novo
Online-Zugang:https://peerj.com/articles/11845.pdf
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