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Loss of magel2, a candidate gene for features of Prader-Willi syndrome, impairs reproductive function in mice.

<h4>Background</h4>MAGEL2 is one of several genes typically inactivated in the developmental obesity disorder Prader-Willi syndrome (PWS). The physiological consequences of loss of MAGEL2, but without the concurrent loss of other PWS genes, are not well understood. Gene-targeted mutation of Magel2 i...

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Autores principales: Rebecca E Mercer, Rachel Wevrick
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2009-01-01
Colección:PLoS ONE
Acceso en línea:https://doi.org/10.1371/journal.pone.0004291
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