Copper-Catalyzed Asymmetric Carboboronation of Allenes to Access α-Quaternary Amino Esters with Adjacent Stereocenters

Summary: Optically active α-quaternary amino acids have received much attention because of the important biomedical applications implicated for compounds containing this structure. Additionally, asymmetric synthesis of highly functionalized chiral α-quaternary amino esters with vicinal stereocenters...

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Principais autores:	Chao-Yang Zhao, Hao Zheng, Ding-Wei Ji, Xiang-Ting Min, Yan-Cheng Hu, Qing-An Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2020-06-01
coleção:	Cell Reports Physical Science
Assuntos:	copper catalysis three-component coupling carboboronation quaternary amino esters enantioselectivity
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S266638642030062X
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