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Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals

Abstract Background 37 million individuals are currently infected with Onchocerca volvulus (O. volvulus), a parasitic nematode that elicits various dermal manifestations and eye damage in man. Disease control is primarily based on distributing ivermectin in mass drug administration (MDA) programmes...

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Principais autores: Kathrin Arndts, Ute Klarmann-Schulz, Linda Batsa, Alexander Y Debrah, Christian Epp, Rolf Fimmers, Sabine Specht, Laura E Layland, Achim Hoerauf
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2015-03-01
Serier:Parasites & Vectors
Fag:
Onchocerca volvulus
Microfilariae
Plasmodium
Cytokine
Ivermectin
MSP-1
Online adgang:https://doi.org/10.1186/s13071-015-0786-5
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