Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals

Abstract Background 37 million individuals are currently infected with Onchocerca volvulus (O. volvulus), a parasitic nematode that elicits various dermal manifestations and eye damage in man. Disease control is primarily based on distributing ivermectin in mass drug administration (MDA) programmes...

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Hauptverfasser:	Kathrin Arndts, Ute Klarmann-Schulz, Linda Batsa, Alexander Y Debrah, Christian Epp, Rolf Fimmers, Sabine Specht, Laura E Layland, Achim Hoerauf
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2015-03-01
Schriftenreihe:	Parasites & Vectors
Schlagworte:	Onchocerca volvulus Microfilariae Plasmodium Cytokine Ivermectin MSP-1
Online-Zugang:	https://doi.org/10.1186/s13071-015-0786-5
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