Dynamics of mutant BCR-ABL-positive clones after cessation of tyrosine kinase inhibitor therapy
Background Point mutations of the BCR-ABL tyrosine kinase domain are considered the predominant cause of imatinib resistance in chronic myeloid leukemia. The expansion of mutant BCR-ABL-positive clones under selective pressure of tyrosine kinase inhibition is referred to as clonal selection; there a...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Ferrata Storti Foundation
2011-03-01
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| Serija: | Haematologica |
| Online pristup: | https://haematologica.org/article/view/5897 |
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