Development and Evaluation of a Physiologically Based Pharmacokinetic Model for Predicting Haloperidol Exposure in Healthy and Disease Populations

The physiologically based pharmacokinetic (PBPK) approach can be used to develop mathematical models for predicting the absorption, distribution, metabolism, and elimination (ADME) of administered drugs in virtual human populations. Haloperidol is a typical antipsychotic drug with a narrow therapeut...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Mohammed S. Alasmari, Fawaz Alasmari, Abdullah F. Alasmari, Aws Alshamsan, Sary Alsanea, Muhammad F. Rasool, Faleh Alqahtani
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-08-01
coleção:	Pharmaceutics
Assuntos:	PBPK PK-Sim<sup>®</sup> haloperidol psychosis personalized medicine
Acesso em linha:	https://www.mdpi.com/1999-4923/14/9/1795
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!