Nanomodified Switch Induced Precise and Moderate Activation of CAR‐T Cells for Solid Tumors

Abstract Chimeric antigen receptor (CAR)‐T cell therapy is a transformative treatment against advanced malignancies. Unfortunately, once administrated in vivo, CAR‐T cells become out of artificial control, and fierce response to CAR‐T therapy may cause severe adverse events, represented by cytokine‐...

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Detalles Bibliográficos

Autores principales:	Xinyue Wang, Fanyan Meng, Xiang Li, Luxin Xue, Anni Chen, Yuling Qiu, Zhifan Zhang, Lin Li, Fengcen Liu, Yishan Li, Zhichen Sun, Yanhong Chu, Ruihan Xu, Lixia Yu, Jie Shao, Manman Tian, Xiaoping Qian, Qin Liu, Baorui Liu, Rutian Li
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2023-04-01
Colección:	Advanced Science
Materias:	cancer immunotherapy cytokine‐release syndrome nanoparticles on‐target/off‐tumor effects chimeric antigen receptor‐T (CAR‐T)
Acceso en línea:	https://doi.org/10.1002/advs.202205044
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