Amyloid spatial extent with florbetapir-PET for early detection of preclinical Alzheimer’s disease

Background: Prevention of Alzheimer’s disease (AD) requires biomarkers sensitive to the earliest amyloid-β (Aβ) deposits. Objectives: To characterize performance of a recently-developed Aβ-PET spatial extent metric (EXT) for early Aβ detection using 18[F]-florbetapir (FBP)-PET, evaluating its sensit...

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Autori principali:	Emma G. Thibault, Grace Del Carmen Montenegro, J․Alex Becker, Julie C․ Price, Brian C. Healy, Bernard J. Hanseeuw, Rachel F. Buckley, Heidi I.L. Jacobs, Michael J. Properzi, Reisa A. Sperling, Keith A. Johnson, Michelle E. Farrell
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2026-05-01
Serie:	The Journal of Prevention of Alzheimer's Disease
Soggetti:	Amyloid PET Preclinical Alzheimer’s disease pTau217 Early detection Amyloid staging
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2274580726000531
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