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Amyloid and tau burden relate to longitudinal changes in the performance of complex everyday activities among cognitively unimpaired older adults: results from the performance-based Harvard Automated Phone Task

BackgroundChanges in everyday functioning constitute a clinically meaningful outcome, even in the early stages of Alzheimer's disease. Performance-based assessments of everyday functioning might help uncover these early changes. We aimed to investigate how changes over time in everyday functioning r...

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Principais autores: Mark A. Dubbelman, Ibai Diez, Christopher Gonzalez, Rebecca E. Amariglio, J. Alex Becker, Jasmeer P. Chhatwal, Jennifer R. Gatchel, Keith A. Johnson, Joseph J. Locascio, Onyinye J. Udeogu, Sharon Wang, Kathryn V. Papp, Michael J. Properzi, Dorene M. Rentz, Aaron P. Schultz, Reisa A. Sperling, Patrizia Vannini, Gad A. Marshall
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-06-01
Serier:Frontiers in Aging Neuroscience
Fag:
Alzheimer's disease
function
instrumental activities of daily living
amyloid
tau
longitudinal
Online adgang:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1420290/full
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