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Vascular smooth muscle cell phenotype switching in carotid atherosclerosis

Carotid plaque instability contributes to large vessel ischemic stroke. Although vascular smooth muscle cells (VSMCs) affect atherosclerotic growth and instability, no treatments aimed at improving VSMC function are available. Large genetic studies investigating atherosclerosis and carotid disease i...

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Principais autores: Elizabeth L. Chou, MD, Christian L. Lino Cardenas, PharmD, MSc, PhD, Mark Chaffin, MS, Alessandro D. Arduini, PhD, Dejan Juric, MD, James R. Stone, MD, PhD, Glenn M. LaMuraglia, MD, Matthew J. Eagleton, MD, Mark F. Conrad, MD, Eric M. Isselbacher, MD, Patrick T. Ellinor, MD, PhD, Mark E. Lindsay, MD, PhD
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-01-01
Colecção:JVS - Vascular Science
Assuntos:
Atherosclerosis
Carotid
Single cell sequencing
Vascular smooth muscle cells
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666350321000456
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