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Vascular smooth muscle cell phenotype switching in carotid atherosclerosis

Carotid plaque instability contributes to large vessel ischemic stroke. Although vascular smooth muscle cells (VSMCs) affect atherosclerotic growth and instability, no treatments aimed at improving VSMC function are available. Large genetic studies investigating atherosclerosis and carotid disease i...

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Autori principali: Elizabeth L. Chou, MD, Christian L. Lino Cardenas, PharmD, MSc, PhD, Mark Chaffin, MS, Alessandro D. Arduini, PhD, Dejan Juric, MD, James R. Stone, MD, PhD, Glenn M. LaMuraglia, MD, Matthew J. Eagleton, MD, Mark F. Conrad, MD, Eric M. Isselbacher, MD, Patrick T. Ellinor, MD, PhD, Mark E. Lindsay, MD, PhD
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2022-01-01
Serie:JVS - Vascular Science
Soggetti:
Atherosclerosis
Carotid
Single cell sequencing
Vascular smooth muscle cells
Accesso online:http://www.sciencedirect.com/science/article/pii/S2666350321000456
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