CD47-SIRPα axis in cancer therapy: Precise delivery of CD47-targeted therapeutics and design of anti-phagocytic drug delivery systems
As a “marker of self”, CD47 is expressed on the surface of all cells in humans, mice, and other mammals to inhibit phagocytic destruction of normal cells through interacting with signal regulatory protein α (SIRPα) on the macrophages and dendritic cells and sending a “don’t eat me” signal. Unfortuna...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2022-09-01
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| Schriftenreihe: | Medicine in Drug Discovery |
| Schlagworte: | |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S2590098622000203 |
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