The longitudinal impact of low-dose morphine on diurnal cortisol profiles in people with chronic breathlessness and chronic obstructive pulmonary disease (COPD): an exploratory study

Abstract Introduction Stress activates the hypothalamic-pituitary-adrenal (HPA) axis of which cortisol is an end product. ‘Allostatic load’ is where systems including the HPA axis are exposed to high, cumulative, physiologic burdens (such as chronic breathlessness) leading to flatter diurnal cortiso...

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Główni autorzy:	Diana H. Ferreira, Richella Ryan, Nina Smyth, Angela Clow, David C. Currow
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2025-04-01
Seria:	Respiratory Research
Hasła przedmiotowe:	Chronic breathlessness Sustained-release morphine Cortisol Palliative care Symptom control
Dostęp online:	https://doi.org/10.1186/s12931-025-03230-9
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