The longitudinal impact of low-dose morphine on diurnal cortisol profiles in people with chronic breathlessness and chronic obstructive pulmonary disease (COPD): an exploratory study

Abstract Introduction Stress activates the hypothalamic-pituitary-adrenal (HPA) axis of which cortisol is an end product. ‘Allostatic load’ is where systems including the HPA axis are exposed to high, cumulative, physiologic burdens (such as chronic breathlessness) leading to flatter diurnal cortiso...

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Autori principali:	Diana H. Ferreira, Richella Ryan, Nina Smyth, Angela Clow, David C. Currow
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-04-01
Serie:	Respiratory Research
Soggetti:	Chronic breathlessness Sustained-release morphine Cortisol Palliative care Symptom control
Accesso online:	https://doi.org/10.1186/s12931-025-03230-9
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