ApoB100 remodeling and stiffened cholesteryl ester core raise LDL aggregation in familial hypercholesterolemia patients

Patients with familial hypercholesterolemia (FH) exhibit a significant residual cardiovascular risk. A new cardiovascular risk factor is the susceptibility of individual LDL particles to aggregation. This study examined LDL aggregation and its relationship with LDL lipid composition and biophysical...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Maria Teresa La Chica Lhoëst, Andrea Martínez, Eduardo Garcia, Jany Dandurand, Anna Polishchuk, Aleyda Benitez-Amaro, Ana Cenarro, Fernando Civeira, Amable Bernabé, David Vilades, Joan Carles Escolà-Gil, Valerie Samouillan, Vicenta Llorente-Cortes
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-01-01
Schriftenreihe:	Journal of Lipid Research
Schlagworte:	familiar hypercholesterolemia LDL aggregation ApoB100 FTIR DSC secondary structures
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0022227524002086
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!