ApoB100 remodeling and stiffened cholesteryl ester core raise LDL aggregation in familial hypercholesterolemia patients

Patients with familial hypercholesterolemia (FH) exhibit a significant residual cardiovascular risk. A new cardiovascular risk factor is the susceptibility of individual LDL particles to aggregation. This study examined LDL aggregation and its relationship with LDL lipid composition and biophysical...

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Detalles Bibliográficos

Principais autores:	Maria Teresa La Chica Lhoëst, Andrea Martínez, Eduardo Garcia, Jany Dandurand, Anna Polishchuk, Aleyda Benitez-Amaro, Ana Cenarro, Fernando Civeira, Amable Bernabé, David Vilades, Joan Carles Escolà-Gil, Valerie Samouillan, Vicenta Llorente-Cortes
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-01-01
Series:	Journal of Lipid Research
Assuntos:	familiar hypercholesterolemia LDL aggregation ApoB100 FTIR DSC secondary structures
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0022227524002086
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