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Replicated chromatin curtails 53BP1 recruitment in BRCA1-proficient and BRCA1-deficient cells

This study demonstrates how single cell normalization to genome size provides insight into genome function, here in the context of DNA double-strand break repair by 53BP1 versus BRCA1–BARD1. DNA double-strand breaks can be repaired by non-homologous end-joining or homologous recombination. Which pat...

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Bibliografiske detaljer
Principais autores: Jone Michelena, Stefania Pellegrino, Vincent Spegg, Matthias Altmeyer
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2021-06-01
Serier:Life Science Alliance
Online adgang:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101023
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