Developing a predictive model for blood-brain-barrier permeability to explore relevance of in vitro neurotoxicity data for in vivo risk assessment
Introduction:Despite recent rapid advancements in in vitro toxicology, its application to whole-body health outcomes remains limited. Incorporating factors like internal exposure, such as permeability across biomembranes, could improve its relevance. Notably, there is a lack of data and predictive m...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2025-04-01
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| Collection: | Frontiers in Toxicology |
| Sujets: | |
| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/ftox.2025.1535112/full |
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