Physicochemical investigation of phenobarbital sodium interactions with anionic bile salt micelles: Binding, partitioning, and micellization behavior

Understanding drug-surfactant interactions is crucial for optimizing pharmaceutical formulations. This study aimed to comprehensively investigate the physicochemical interactions between phenobarbital sodium (PS) and two anionic bile salts, sodium cholate (NaC) and sodium deoxycholate (NaDC), in aqu...

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Bibliografske podrobnosti

Principais autores:	Haytham Abuissa, Ashraf EL-Hashani
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-07-01
Serija:	Next Materials
Teme:	Bile salts Critical Micelle Concentration (CMC) Interfacial parameters Binding constant Partition coefficient
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2949822825003922
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