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Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation

Abstract Background Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Recently, a case was encountered in which the blood concentration of tacrolimus (TCR) at steady state increased after intravenous MTX adm...

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Principais autores: Chiaki Inoue, Takehito Yamamoto, Hiroshi Miyata, Hiroshi Suzuki, Tappei Takada
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2023-12-01
Series:Journal of Pharmaceutical Health Care and Sciences
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Acceso en liña:https://doi.org/10.1186/s40780-023-00306-w
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